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Internationally, letting tumors grow too large on mouse models comes under crelty.
3Rs
Replace: With other models
Reduce: As few as possible experiments (share more to reduce redundancy)
Refine: Minimize stress in animals.
心血管系统，和心血管疾病的危害因素。CDV动物模型，CDV研究的动物模式选择伦理问题。
